I'd like to take this time to apologize to my family, friends, and specifically my roommate. Over the last few months (OK, maybe longer) I have been theorizing to anyone who would listen what the new Spider-Man: No Way Home trailer will tell us about the next phase of the MCU. And now that it is here, I can stop bugging my loved ones and make one professional theory for all to hear.
And no, my theory isn't that the former Spider-Men (Tobey Maguire and Andrew Garfield) will return to No Way Home. I do think that will happen, don't get me wrong, there are too many villains returning for the multiverse to not deliver that.
What I want to draw your attention to is one moment that you may have been missed in the trailer. During the scene where Doctor Strange is casting the spell to make the world forget that Peter Parker is Spider-Man, something seems to go catastrophically wrong. (Sidebar: Doctor Strange would not have done this if he didn't see a future in which casting the spell was a better outcome than not, but we can get into that at a different time.)
What I would like to argue is that this exact moment was not caused by Peter Parker, but rather the same Nexus event that happened at the end of Loki that caused all the branching timelines to occur. You remember... this one.