"Who's driving? Oh my god, bear is driving! How can that be?" from the Clerks animated series. It comes up far more often than you would think.

https://www.youtube.com/watch?v=pBw7KE8wDSo

There are tons more, I'm sure, but this is what immediately sprang to mind.

I use Dumb and Dumber’s “our pets heads are falling off!!!!” whenever something goes especially wrong. Makes me laugh every time

I quote The Simpsons, both in context of what is happening or completely random. No one is safe from me and my Simpsons quotes. 

The classic Game of Thrones quote: "I know death. It wears many faces." except I use it whenever my friends ask me to go to Chipotle with them. 

Still trying to figure out how to use, “I’m stuck in an ATM vestibule with Jill Goodacre” in a regular conversation, but I enjoy saying it to myself every once in awhile. 

Otherwise, I love “Hang onto your butts,” and I’m basic enough to say “workin’ on my night cheese” too often. 

What quotes do you use in regular life, whether or not anyone understands them?

“A day might come when [enter some innocuous thing we normies face]. But today is not that day.” 

What TV and movie quotes do you find yourself using in your daily life?